Cubebin is a dibenzyl butyrolactone lignan and also an AChE inhibitor.
Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g
Availability: In stock

Store under frozen or refrigerated conditions, keep away from strong light and heat.

[1]. Syed RU, et al. Effect of cubebin against streptozotocin-induced diabetic nephropathy rats via inhibition TNF-α/NF-κB/TGF-β: in vivo and in silico study. Sci Rep. 2025;15(1):4369. Published 2025 Feb 5. [2]. Bastos JK, et al. Anti-inflammatory activity of cubebin, a lignan from the leaves of Zanthoxyllum naranjillo Griseb. J Ethnopharmacol. 2001;75(2-3):279-282. [3]. Hirata N, et al. Mechanism of the melanogenesis stimulation activity of (-)-cubebin in murine B16 melanoma cells. Bioorg Med Chem. 2007;15(14):4897-4902. [4]. Niwa AM, et al. Evaluation of lignan (-)-cubebin extracted from Piper cubeba on human colon adenocarcinoma cells (HT29). J Toxicol Environ Health A. 2016;79(2):92-100. [5]. eixeira TR, et al. Cubebin, a Lignan Isolated from Drimys andina, Exhibits Potent and Selective Antiparasitic Activity against Angiostrongylus cantonensis. ACS Omega. 2025 Jul 11;10(28):31161-31169. [6]. Wan M, et al. Cubebin alleviates chronic stress-induced depression-like behavior in mice by regulating the gut microbiome. Eur J Pharmacol. 2025;994:177384. [7]. Patil, S., et al. (2025). Cubebin and Its Derivatives in Neurodegenerative Diseases and Their Antimicrobial Potential. In: Mukherjee, B. (eds) Dietary Supplements and Nutraceuticals.